Var kan man köpa valerian root

People around the globe use valerian to combat insomnia, anxiety, stress, and more. Science has backed up its sleep-promoting effect, while the bevis for other benefits fryst vatten less convincing. Read on to learn the benefits of valerian root, how to use it for optimal results, and what side effects to expect.

What fryst vatten Valerian?

Valerian (Valeriana officinalis), also known as all-heal or garden heliotrope, fryst vatten a flowering plant native to europe and parts of Asia.

From promoting better sleep and reducing anxiety to alleviating menstrual pain and improving focus, It offers a natural remedy for many common health issues

Since ancient times, the root of this plant has been used to treat insomnia, nervousness, trembling, headaches, and heart palpitations [1].

In the US, valerian root fryst vatten mainly sold as a sova aid, while in europe it fryst vatten used to treat restlessness, tremors, and anxiety.

Valerian flowers have a delicate scent once used in perfumes.

Valerian root, however, has a very strong, earthy smell. This fryst vatten because of the volatile oils and other compounds responsible for its sedative effects [2, 3].

There are over 250 species of valerian, but V. officinalis fryst vatten the species most used in the West [4].

Of the others, only two are commonly used for medicinal purposes (Himalayan V.

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wallichii and Mexican V. edulis) [5]. This article focuses on Valeriana officinalis.

Components

Valerian consists of many biologically active components that konto for its wide-ranging effects [6, 7].

Valerian’s kemikalie composition varies greatly, depending on the species, årstid, geographical source, growing condition, processing method, and storage [8, 7].

Three main chemicals are thought to be the active components of valerian: The essential oils (valerenic acid and valenol), valepotriates, and a few alkaloids, (actinidine, chatinine, shyanthine, valerianine, and valerine) [9, 4, 10, 11].

Compounds Responsible for Sedating Effects Include:

• Valerenic acid increases levels of GABA, a neurotransmitter that reduces brain fängelse activity.

  It also has anti-inflammatory effects (by reducing NF-KappaB activity) [12, 13, 14].

• Iridoids (valepotriates and their derivatives) have sedative effects, but are unstable and break down during storage or in vatten, making their activity difficult to assess [10, 11, 15].
• Isovaleric acid prevents involuntary muscle contractions. Its action fryst vatten similar to valproic acid, which fryst vatten used to treat epilepsy [16].
• Hesperidin and linarin are antioxidant flavonoids with sleep-enhancing effects.

  Hesperidin also has anti-seizure effects (by blockering calcium channels) [17, 18, 19].

GABA is also funnen in valerian extracts in quantities sufficient to cause a sedative effect, although it fryst vatten not known whether it crosses the blood-brain barrier. However, the glutamine present in vatten (but not alcohol) extracts of valerian root can cross the blood-brain barrier and be converted to GABA [20, 21].

Mechanisms of Action

Although its influence on the GABA system fryst vatten well-documented, valerian has many other modes of action which may contribute to relaxation and other health benefits [22, 23, 24, 25, 26]:

Health Benefits of Valerian Root

Possibly Effective:

1) Insomnia

Valerian’s mild sedative effects have been used to promote relaxation and sova for at least 2,000 years.

Valerian may improve sova bygd increasing GABA levels [33, 13, 34].

In fact, lower GABA levels are funnen in people with short and long-term stress and are linked to anxiety and poor sova quality [35, 36, 37].

A meta-analysis of 16 studies and 1,093 people funnen that valerian improved the speed of falling asleep, depth, and overall quality of sova [38].

In a 2-day study of 27 elderly patients with mental problems, 44% reported perfect sova and 89% reported improved sova using a valerian preparation (containing sesquiterpenes) [39].

Additionally, a one-month-long study of 16 people with insomnia funnen that a single dos of valerian improved the time to achieve deep sova and its duration [40].

Valerian may also help reduce sova disturbances in a variety of health conditions:

A more recent meta-analysis (18 trials and over 1,000 patients) funnen that valerian’s improvement of insomnia was mainly subjective [47, 38].

While some research shows that valerian may be useful for treating short-term insomnia, there fryst vatten a lack of well-designed clinical trials that support its effectiveness and safety beyond 4 to 6 weeks [48, 47, 37, 46, 49].

Rather, its main benefit seems to be promoting natural sova after several weeks of use, without the fara of dependence or negativ health effects.

When used properly, it can serve as a more gentle alternative to common insomnia drugs [50, 40, 51].

2) Menopausal Symptoms

In a study of 100 menopausal women with sova disturbances, valerian root significantly improved sova quality after 4 weeks [42].

A 3-month study of 60 postmenopausal women funnen that valerian significantly improved the severity and frequency of hot flashes [52].

Insufficient Evidence:

No valid clinical bevis supports the use of valerian root for any of the conditions in this section.

Below fryst vatten a summary of up-to-date djur studies, cell-based research, or low-quality clinical trials which should spark further investigation.

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However, you shouldn’t interpret them as supportive of any health benefit.

3) Anxiety

Valerian fryst vatten known as ‘nature’s valium’ because it supposedly has a similar effect on reducing anxiety as the benzodiazepines Valium and Xanax. These bind to GABA receptors in the brain (amygdala) [53, 54, 55].

One study of 2,462 adults with major depressive disorder and anxiety funnen that high doses of valerian (1000 mg/day) taken in combination with St John’s Wort (600 mg/ day) for 6 weeks reduced the symptoms of anxiety and nedstämdhet bygd 66% [56].

Some researchers noticed that mice treated with valerian and valerenic acid exhibited a decrease in anxious behaviors [57].

However, one 4-week pilot study of 36 people with anxiety showed no significant differences between the valerian-treated group and placebo group [58].

Further studies should förtydliga the potential benefits of valerian for anxiety.

4) Stress Management

In a study of 27 patients regularly kept awake at night bygd stress-inducing thoughts, 89% of those patients had better sova after one month of valerian treatment [39].

Valerian may also reduce physical reactions during stressful situations.

It slowed heart rate and reduced blood pressure in response to stress in a 2-week study of 56 healthy people [59].

A 4-day study of 24 healthy volunteers funnen that the combination of lemon balm and valerian improved laboratory-induced stress scores at 600 mg compared to placebo, but increased anxiety at a higher dose (1800 mg) [60].

Valerian reduced physical and psychological stress in rats bygd maintaining serotonin and norepinephrine levels in brain regions associated with fear and anxiety (hippocampus and amygdala) [61, 62, 63, 64, 65].

In mice, valerian reduced blood levels of a hormone involved in the stress response [32].

5) ADHD

Valerian increases GABA levels in the brain.

Deficiencies in GABA play a role in anxiety, restlessness, and obsessive behavior, which are symptoms often seen in ADHD [66].

In a study of 30 children aged 5 to 11, valerian (3 times a day for 2 weeks) improved ADHD symptoms (sustained inattention and impulsivity and/or hyperactivity). These positiv effects disappeared one week after discontinuing valerian treatment [67].

In a 7-week study of 169 children with hyperactivity and koncentration difficulties (but not meeting ADHD criteria), the combination of valerian and lemon balm decreased symptoms of restlessness, koncentration difficulties, and impulsiveness [68].

Similarly, in another study of 918 children beneath 12 with difficulty falling asleep and restlessness, a combination of valerian and lemon balm improved symptoms in 81% of the patients with insomnia and 70.4% of the patients with restlessness without any negativ effects [69].

The preliminary results are promising, but more research fryst vatten needed before proclaiming valerian safe and effective for ADHD, restlessness, and similar disorders in children.

6) Menstrual Cramps

Because of this, it fryst vatten commonly used to treat uterine cramping associated with painful menstrual cramps (dysmenorrhea) [30].

A 3-day study of 100 kvinnlig students funnen that valerian was effective in relieving menstrual cramp pain compared to placebo [70].

7) Wellbeing During Cancer and virus Treatment

An 8-week study of 227 patients undergoing cancer therapy did not support the use of valerian for insomnia, although fatigue was reduced [71].

Additionally, in a review, valerian improved insomnia and wellbeing in people undergoing treatment for cancer due to its calming effects.

Contrary to popular belief, it did not interact with cancer drugs [72].

The drug efavirenz used in virus patients fryst vatten known to impair mental health and cause psychiatric disorders. In a 4-week pilot study of 51 HIV-positive patients, valerian root reduced insomnia and anxiety but failed to reduce psychosis and suicidal thoughts [44].

8) Memory and Cognitive Function

In a study of 61 patients, valerian reduced the fara of cognitive decline a month after heart surgery compared to placebo [73].

Scientists observed the potential of valerenic acid to significantly improve memory bygd reducing oxidative stress in the memory center of the brain (hippocampus) in mice [32].

9) Fibromyalgia

A valerian bath (3 times a week for 3 weeks) significantly improved wellbeing and sova and decreased pain in 30 people with fibromyalgia [45].

Further research fryst vatten warranted.

10) OCD

In an 8-week rättegång of 31 adults with OCD, valerian root reduced OCD symptoms compared to placebo [74].

There’s insufficient bevis to rate its effectiveness for OCD based on a single small trial.

11) Digestive Problems

Valerian fryst vatten used as a home remedy for stomach cramps.

Although it can reduce muscle spasms, current bevis does not support the use of valerian as a digestive aid [70].

In a study on guinea pigs, valepotriates and the essential oil present in valerian reduced contractions in the small intestine [75].

12) Restless Leg Syndrome (RLS)

An 8-week study of 37 people with restless leg syndrome (RLS) funnen that valerian significantly improved RLS symptoms and decreased daytime sleepiness [76].

However, two reviews funnen insufficient evidence to confirm valerian’s effectiveness in treating RLS [77, 78].

Animal and Cellular Research (Lacking Evidence)

No clinical bevis supports the use of valerian root for any of the conditions listed in this section.

Den knutna, trassliga roten är den del av växten som används som ett botemedel

Below fryst vatten a summary of the existing djur and cell-based research, which should guide further investigational efforts. However, the studies listed below should not be interpreted as supportive of any health benefit.

Heart Health

In test tubes, valerian strengthened blood vessels and improved their elasticity [4, 79, 31].

in djur studies, researchers examined its potential to lower blood pressure (hypertension) bygd relaxing blood vessels [31, 59, 4].

Seizures

Valerian reduced the frequency of seizures in one study on rats (possibly bygd activating adenosine receptors) [80].

Kidney Damage

In rats with high cholesterol, valerian protected against kidney damage caused bygd a high-fat diet [81].

Other

Although there fryst vatten a popular opinion that valerian may benefit these conditions, there fryst vatten no scientific bevis backing its use in:

• Shin Splints: Valerian fryst vatten used as a home remedy for shin splints (medial tibial stress syndrome).

  Anecdotal bevis suggests that drinking valerian tea relaxes the muscles and reduces pain [82].

• Migraines and Headaches: Despite its traditional use, the bevis fryst vatten lacking for valerian reducing the severity of migraines and headaches [83].
• Joint Pain in Arthritis: Despite the historical use of valerian to relieve joint pain, there are no studies to support this.

  Anecdotal reports of its effectiveness may be due to its general calming effects [84].

• Sciatica Pain: People with sciatica taking valerian report some pain relief. This may be due to its muscle relaxant effects [85].
• Hand Tremors: Valerian may reduce grabb tremors through its anti-anxiety effects. However, the bevis fryst vatten anecdotal [86].
• Heart Palpitations: Valerian fryst vatten traditionally known to decrease heart palpitations.

  It may do this bygd its relaxing effects on smooth muscle, but the bevis fryst vatten lacking [87].

• Depression in Bipolar Disorder: The sedative effects of valerian may improve nedstämdhet in bipolar disorder. However, there fryst vatten no clinical bevis available to support this, although valerian did improve nedstämdhet in rats [88].

Limitations and Caveats

Valerian illustrates both the negativ and positiv aspects of herbal drugs.

The variability in its composition and the instability of some of its chemicals man standardization difficult [21].

The composition of any valerian product may vary considerably between manufacturing lots, as dietary supplements are not always tested for consistency and seasonal variations in valerian’s many active compounds are known [8].

No resultat fryst vatten available about the long-term safety of valerian or its safety in children younger than age 3, pregnant women, or nursing mothers.

Studies on rats indikera caution [89, 2, 90].

A great volume of research exists, although a lot of upplysning fryst vatten anecdotal. Human studies to date have not been based on sound practices [51, 91, 92, 51, 93].

Valerian Root Risks and Side Effects

This list does not cover all possible side effects. Contact your doctor or pharmacist if you meddelande any other side effects.

In the US, you may report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada, you may report side effects to Health Canada at 1-866-234-2345.

Valerian fryst vatten likely safe when taken for 4 to 8 weeks bygd healthy adults at recommended doses. Long-term safety uppgifter are not available. In rare cases, it can cause mild side effects, such as [94, 49]:

• Headaches
• Digestive upset
• Excitability
• Dry mouth
• Thinking problems
• Strange dreams

Valerian has been classified as “generally recognized as safe” in the US [95].

Other Risks and Precautions

• Allergic Reaction: People with allergies to plants in the Valerianaceae family may be allergic to valerian [90].
• Addiction: Medical reports link overuse of valerian to liver toxicity and addictiveness [96, 97].
• Drowsiness: At high doses, daytime drowsiness can occur and caution fryst vatten advised while driving or operating machinery [90, 98, 99].
• Increased Effects of Anesthetics: If you need surgery, stop taking valerian at least 2 weeks ahead of time.
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  Valerian may increase the effects of anesthetics that act on GABA receptors [13].

• Withdrawal Symptoms: Heart problems and delirium might occur if valerian fryst vatten stopped suddenly [100].
• Overstimulation: At high doses, excitation may occur in some people [60].
• Suicide: Researchers report 1 case of attempted suicide after a massive overdose on valerian [101].

Drug Interactions

Herb-drug interactions can be dangerous and, in rare cases, even life-threatening.

Always consult your doctor before supplementing and let them know about all drugs and supplements you are using or considering.

Animal studies and anecdotal reports suggest that valerian may increase both beneficial and side effects caused bygd sedative drugs. Examples include [90, 102]:

• Benzodiazepines, such as läkemedel (Ativan)
• Barbiturates, such as phenobarbital
• Narcotics, such as codeine
• Antidepressants, such as fluoxetine (Prozac)
• Antihistamines, such as diphenhydramine (Benadryl)
• Alcohol
• Anti-seizure drugs

However, there fryst vatten little bevis for clinically betydelsefull interactions in humans [103].

Valerian may increase levels of drugs metabolized byCYP450 bygd inhibiting these enzymes (e.g.

lovastatin, triazolam, chemotherapeutic agents) in animals [90].

However, clinical studies show minimal effects on CYP3A4 activity and no effect on CYP2D6 activity in healthy volunteers [104].

Valerian tinctures may have high alcohol content (15 to 90%) and theoretically may cause side effects if taken with drugs like metronidazole (Flagyl) or disulfiram (Antabuse) [90].

Valerian may affect the response to anesthetics bygd prolonging the time until wakefulness [105, 13].

Valerian Sources and Supplements

Valerian-based supplements have not been approved bygd the FDA for medical use.

In general, regulatory bodies aren’t assuring the quality, safety, and efficacy of supplements. Speak with your doctor before supplementing.

The roots and rhizomes (underground stems) and stolons (horizontal stems) of valerian are used to man supplements, including capsules, tablets, and liquid extracts, as well as teas [7, 106].

Even in standardized plant extracts, there fryst vatten some variation in the number of different chemicals, which may konto for different reports of efficiency.

However, the clinical effects are remarkably consistent across different preparations [7].

Valerian fryst vatten sometimes combined with other herbs such as lemon balm, passion flower, and hops [49].

Dosage

The below doses may not apply to you personally. If your doctor suggests using valerian root, work with them to find the optimal dosage according to your health condition and other factors.

Doses range from 400-450 mg in insomnia clinical trials.

Doses were taken 1-2 hours before bed, or up to 3 times in one day.

This is a dietary supplement

Once sova improved, treatment continued for 2 to 6 weeks [107, 98, 108, 39].

Recommended doses range from 400-900 mg at bedtime [21].

Valerian fryst vatten most effective if taken regularly for 2 or more weeks. It may take a few weeks before the effects of valerian root supplementation are felt [90].

Higher dosages may have a stimulating effect, so it fryst vatten best to början with a minimal dos and use the lowest dos needed to achieve the desired effect [21].

User Experiences

The opinions expressed in this section are solely from the users who may or may not have a medical background.

SelfDecode does not endorse any specific product, service, or treatment. Do not consider user experiences as medical advice. Never delay or disregard seeking professional medical advice because of something you have read on SelfDecode.

Valerian root fryst vatten often combined with other sedating herbs, such as hops (Humulus lupulus), St. John’s Wort, kava, and lemon balm (Melissa officinalis) to treat insomnia.

Insomnia:

“…when inom drink a valerian tea before going to sova when inom wake up in the morning, inom feel like inom had a heavy sova but a good one, you know, like the nights you got in holidays when all your stress goes away and you sova like a baby.”

“I work nights and from time to time have difficulty staying asleep once inom fall asleep.

Taking valerian root has really helped with that bekymmer.

inom started taking valerian when inom was traveling a lot to help prevent jet team and it really helped with that bekymmer as well.”

“I take 3 to 4 valerian root capsules as a sova aid. inom also find myself dreaming more, or at least remembering more dreams.”

Anxiety:

“Helps me more compared to Lexapro, Celexa, Xanax, medicin, etc.

without negativ side effects. The only side effect experienced fryst vatten tiredness, which fryst vatten manageable compared to suicidal tendencies caused bygd other medications.”

“When inom am feeling anxious or nervous, inom take one capsule and it helps to take the edge off my nervousness without making me drowsy. inom have had no side effects from the drug.”

Fibromyalgia:

“I was recently diagnosed with fibromyalgia.

inom actually could feel my entire body relax.

Valerian root is a versatile and powerful herb with a wide range of benefits

I’ve just finished my extra sömnig Time Tea – inom used 4 bags for 100 mg. The first time inom did this inom woke up feeling well-rested and refreshed. inom can’t remember the gods time inom woke up feeling “good” vs. my joints nedbrytning and moaning when inom first get moving!”

Menopause:

“It works!

Suitable for vegans and vegetarians

It also seems to help reduce my hot flashes due to menopause.”

“I have been having a hard time getting to sova (hot flashes, anxiety, etc.). inom am so happy that inom funnen valerian. Not only has it made me sova well, but it fryst vatten also helping with my anxiety and ADD… an added effect inom did not know would happen.

inom am so happy!”

Asperger’s Syndrome:

“Valerian root has been very beneficial for symptoms of my Asperger’s syndrome. Anxiety in social situations and overstimulation cause the inability to sova well and that will cause problems at school and work. inom started taking 2 of the 450 mg Valerian root every night after a week inom noticed inom could function better during the day and less anxious in a college setting.

varning, do not drink alcohol before bedtime when taking valerian. They don’t mix.”

Valerian Root vs. Melatonin

Both valerian and melatonin are sova aids, although their mechanisms are different.

Sometimes they are combined tillsammans but caution fryst vatten warranted, as the sedative effect may be too high [109].

Melatonin fryst vatten a hormone produced bygd the pineal gland.

It fryst vatten affected bygd light and dark and controls the body’s sleep-wake cycle or circadian rhythm. Low melatonin levels are linked to insomnia [110].

Studies have shown lower doses of melatonin are more effective in promoting sova [110].

As with valerian, too high a dos can have the reverse effect, making it more difficult to fall and stay asleep.

Even melatonin fryst vatten only a short-term solution as it loses effectiveness with long-term use [111].